What’s tested

Using a single, nonfasting tube of serum, the ELF Score is obtained from an algorithm that incorporates 3 direct markers of fibrosis:

  • Hyaluronic acid (HA)

     Extracellular matrix (ECM) component

  • Procollagen III N-terminal peptide (PIIINP)

      ECM component

  • Tissue inhibitor of metalloproteinase 1 (TIMP-1)

     Inhibits breakdown of collagen III

The score result identifies risk of disease progression to cirrhosis or LREs.

ªIn the Mid group, the risk of disease progression is similar to the pre-test risk. Pre-test risk refers to the likelihood of disease progression in the overall intended use population without considering the ELF Score. Results should always be interpreted in c